Studies on Mastication Stage Binding of Antioxidants

Spectroscopic Studies on Titanium Ion Binding to the Apolactoferrin

Titanium (Ti) is a relatively abundant element that has found growing applications in medical science and recently some of Ti compounds are introduced as anticancer drugs. In spite of very limited data which exist on the Ti metabolism, some proteins might be involved in the mechanism of action of Ti. Up to our knowledge, there is not any report in the literature concerning binding of Ti to apol...

Textural properties of food used in studies of mastication.

Foods are known to influence jaw elevator muscle activity in chewing. With the long-range goal of gaining insight into force control and modeling muscle recruitment, these initial experiments were performed to determine the textural properties of commonly used test food. Experiments were carried out by means of a standard Instron instrument, equipped with a compression cell. A stylus with 45-de...

Spectroscopic and Molecular Docking Studies on DNA Binding Interaction of Podophyllotoxin

The binding interaction of novel podophyllotoxin derivative, (3R,4R)-4-((benzo[d][1,3]dioxol-5-yl)methyl)-dihydro-3-(hydroxy(3,4-dimethoxyphenyl) methyl) furan-2(3H)-one (PPT), with calf thymus DNA (ctDNA) has been examined using UV-Visible absorption spectrophotometry, fluorescence spectroscopy, viscosity measurement and molecular docking studies. UV-Vis absorption results showed hyperchromic ...

Molecular Modeling Studies on Vinblastine Binding Site of Tubulin for Antimitotic agents

Medicinal chemistry depends on many other disciplines ranging from organic chemistry andpharmacology to computational chemistry. Typically medicinal chemists use the moststraightforward ways to prepare compounds. The validation of any design project comes from thebiological testing.Studies of the binding site of vinblastine by a single cross—linking experiment identified it asbeing between resi...

Studies on the Binding